Comparison of the DAS28-CRP and DAS28-ESR in patients with rheumatoid arthritis

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Comparison of Activity Score DAS28-ESR and DAS28-CRP in Moroccan Patients with Rheumatoid Arthritis

Background: Disease Activity Score-28 joints (DAS-28) is nowadays the gold standard for measuring the disease activity in patients with RA. The original DAS-28 was based on erythrocyte sedimentation (ESR), but an alternative formula incorporating C-reative protein (CRP) [DAS-28(CRP)] has been developed. Objectives: To compare the disease activity score DAS28-ESR versus DAS28–CRP, and to determi...

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DAS28-CRP and DAS28-ESR cut-offs for high disease activity in rheumatoid arthritis are not interchangeable

BACKGROUND In most patients with rheumatoid arthritis (RA), Disease Activity Score 28-joint count C reactive protein (DAS28-CRP) is lower than DAS28 erythrocyte sedimentation rate (DAS28-ESR), suggesting that use of the DAS28-ESR cut-off to assess high disease activity (HDA) with DAS28-CRP may underestimate the number of patients with HDA. We determined the DAS28-CRP value corresponding to the ...

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CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients

INTRODUCTION Single-nucleotide polymorphisms (SNPs) in the CRP gene are implicated in the regulation of the constitutional C-reactive protein (CRP) expression and its response to proinflammatory stimuli. Previous reports suggest that these effects may have an impact on clinical decision-making tools based on CRP, such as the Disease Activity Score in 28 joints (DAS28). We aimed to investigate t...

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Applying low disease activity criteria using the DAS28 to assess stability in patients with rheumatoid arthritis.

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ژورنال

عنوان ژورنال: International Journal of Rheumatic Diseases

سال: 2015

ISSN: 1756-1841

DOI: 10.1111/1756-185x.12695